Botox
Inventors: Alastair and Jean Carruthers
Year: 1987
What Happened: The couple were using small doses of a deadly toxin to treat ‘crossed eyes’ eyelid spasms and other eye-muscle disorders when they noticed an interesting side effect.
Big Discovery: Wrinkles magically disappeared.
As a Result: The expressionless face became the ‘it’ look, thanks to Botox.